In case of skin contact wash off with soap and plenty of water. Ghs classification in accordance with 29 cfr 1910 osha hcs. No smoking p233 keep container tightly closed p240 groundbond container and receiving equipment. Upload files that contain software or other material protected by intellectual property laws or by rights of privacy of publicity unless you own or control the rights thereto or have received all necessary consents. Acetonitrile in water 20%, s4b thermo fisher scientific. P210 keep away from heat, sparks, open flames, hot surfaces. Ghs label generator create and download oshacompliant. Acetonitrile is a mediumpolarity solvent that is miscible with water. Ghs harmonizes most classification criteria for supply and transportation and is. For use on containers that store acetonitrile to ensure the workplace is aware of the immediate chemical hazards that are present. Ghs compliant sds documents with ghsauth, a free software tool. Airgas usa, llc and its affiliates 259 north radnorchester road. This msds has been prepared according to the hazard criteria of the controlled products regulations cpr and. In order to create safety data sheets sdss for your products, you need to comply with regulations such as ghs which is the globally harmonized system of classification, labelling and packaging of substances and mixtures.
Harmful by inhalation, in contact with skin and if swallowed. Logicsds, the easiest to use expert sds software for ghs. The ghs is not in itself a regulation or legal obligation, but can become one when an individual regulatory authority issues a rulemaking to align its own hazard. This reagent is intended for nterminal protein sequencing applications. Relevant identified uses of the substance or mixture and uses advised against.
Chemical safety has spent the better part of this year building, maintaining and updating a database of safety data sheets by the largest manufacturers and suppliers of life science and specialty chemicals. Safety data sheet according to 29cfr19101200 and ghs rev. With more than 15,000 users and 8 million covered employees, msdsonline solutions from velocityehs are the leading costeffective, cloudbased tools that help thousands of businesses across a variety of industries manage global hazard communication hazcom regulatory compliance requirements when you partner with velocityehs, you partner with a pioneering innovator. We enable science by offering product choice, services, process excellence and our people make it happen. Acetonitrile is expected to weakly adsorb to most soils based on the koc value. Classify chemical substances, raw materials, and sds labeling with this highly. Safety data sheet sds acetonitrile, 15% solution 01. In a wellconducted study in mice, the oral ld50 of acetonitrile was calculated to be 617 mgkg. It is a compilation of practical, understandable information designed to guide the reader in responsible handling of acetonitrile, and to answer commonly raised questions about acetonitrile safety. Sds msds database search safety data sheets library.
Identification of the substancemixture and of the companyundertaking. Check availability and compare product details acetonitrile chromasolv plus, for hplc. Logicsds, the sds software enables sds msds editing in any language and in the ghsclp and ghsus regulations. Disposal must be made according to official regulations. It is used in all the analytical laboratories as a major component of mobile phase in high performance liquid chromatography hplc and in liquid chromatography mass spectrometry lcms. Acetonitrile is a common twocarbon building block in organic synthesis of many useful chemicals, including acetamidine hydrochloride, thiamine, and. Ghs global harmonized standard compliant sds safety data sheet authoring software. Volatilization from soil surfaces and leaching into ground water is expected to be significant. Cas acetonitrile acetonitrile ccn msds toxicity property. Reach optimal ghs compliance with uls ghs professional software platform. Methanol and the click the search button, click on the sds button. Training finding and understanding sds and ghs labels. Learn more about acetonitrile osha ghs label, hcl labels.
Inhalation move casualty to fresh air and keep at rest. Method 1606, issue 3, dated 15 january 1998 page 3 of 3 niosh manual of analytical methods nmam, fourth edition c w f w b b f b b v, mgm3 in the calibration range step 9. Made from 2 mils polyester and a 1 mils gloss polyester laminate. May react vigorously with strong oxidizing reagents, sulfuric acid, chlorosulfonic acid, sulfur trioxide, perchlorates, nitrating reagents, and nitric acid. Firstaid measures eyes rinse with plenty of water for at least 15 minutes and seek medical attention immediately. Acetonitrile is a ligand in many transition metal nitrile complexes. Three volunteers were exposed for 4 hours at 40, 80, or 160 ppm acetonitrile. Sigmaaldrich offers a number of acetonitrile products.
First aid measures general advice consult a physician. Chemical analysis toxic analysis chemical substance property information, catalog of supplier manufacturer distributor and custom synthesis oganic synthesis biosynthesis companies for raw material laboratory reagent equipment solution intermediate specialty chemicals and so on. Acetonitrile metabolizes into cyanide over 2 to 8 hours, so symptoms or signs of toxicity may be delayed after significant exposures. Ghs sds authoring software can help you automate the authoring process so that your documents comply with such regulations. At 40 ppm, odor was detected, after which olfactory fatigue was noted. Enviromsds ghs sds software for sds authoring and sds.
For use on containers that store acetonitrile eluent to ensure the workplace is aware of the immediate chemical hazards that are present. Upload files that contain viruses, corrupted files, or any other similar. General description acetonitrile, an aliphatic nitrile, is widely used as an organic solvent and intermediate in organic syntheses. Page 55 safety data sheet sds acetonitrile, 15% solution. Create ghs labels that are oshacompliant quickly and easily. Cas 75058 acetonitrile for gas chromatography ms suprasolv. Disposal considerations waste treatment methods product.
Designed to stick to oily, greasy or irregular surfaces. Ace acetic acid nitrile cyanomethane ethane nitrile ethyl nitrile methane carbonitrile methyl cyanide. Consider cyanide antidote as clinically indicated, such as sodium thiosulfate and sodium nitrate. Registration number 75 05 8 200 835 2 608 001 00 3 01 2119477 38 xxxx 4. Before handling, always consult a current materials safety data.
Since sds writing is the final step, logic sds provides the possibility to use the ghsclp calculation module alone and to print product ghsclp labels. Acetonitrile ch 3 cn, cas 75058, also known as methyl cyanide or cyanomethane, is the simplest organic nitrile. Ethyl nitrile recommended use laboratory chemicals. Acetonitrile msds material safety data sheet or sds, coa and coq, dossiers, brochures and other available documents.
Harmonized system of classification and labeling of chemicals ghs. For instant, acetonitrile, methanol, and dichloromethane are common eluents in. Enviromsds is the premier sds software and document management and archival software for authoring, managing, tracking and distributing multilingual sds and hazard labels for a corporate wide solution. Safety data sheet, toxicological data, globally harmonised system ghs, laboratory hazards and risks, laboratory safety. Acetonitrile, for hplc solvent is a colorless liquid used in chemical labs as a polar aprotic solvent in organic synthesis. Acetonitrile cas 75058 hplc, meets acs specifications, meets reagent specifications for testing. Show this safety data sheet to the doctor in attendance. Acetonitrile is utilized as a polar aprotic solvent in organic synthesis, and in the purification of butadiene. This value indicates that acetonitrile will not significantly bioconcentrate in aquatic organisms or adsorb to suspended solids and sediments in water. Industrially, it is used as a solvent in the purification of butadiene and in the manufacturing of photographic film. Ghsauth by markov computer systems is an easy to use software tool for authoring global harmonized standard ghs compliant safety data sheet sds documents and safety labels.
Dispose of waste in accordance to applicable national, regional, or. Compliant with the osha hazard communication standard 1910. Dispose of waste in accordance to applicable national, regional, or local regulations. Cyanobearing indolinones by oxidative arylalkylation of olefins in the presence of palladium catalyst. Further, acetonitrile can also be used as the solvent in the process of producing synthetic fiber and special paints. Is a free sds and ghs label database a useful tool for your organization.
Produced mainly as a byproduct of manufacturing acrylonitrile, acetonitrile is a colorless liquid with an etherlike odor. Free safety data sheets and ghs labels ehs software. Its reaction with cyanogen chloride affords malononitrile. Hazards identification medical conditions aggravated by overexposure preexisting disorders involving any target organs mentioned in this msds as being at risk may be aggravated by overexposure to this product no known significant effects or critical hazards. Volitization from soil surfaces and leaching into ground water is expected to be significant. Acetonitrile decomposes when heated to produce deadly toxic hydrogen cyanide gas and oxides of nitrogen. Below you will find the updated section 2 of the eu ghs sds for acetonitrile. If inhaled if breathed in, move person into fresh air.
Acetonitrile hplc, fisher chemical fisher scientific. Safety data sheet northwest missouri state university. It is transparent to uvvisible light, which makes it highly applicable in spectrophotometric and fluorimetric techniques. Acetonitrile is unreactive towards photochemicallygenerated free radicals and direct photolysis in the gaseous phase. H225 highly flammable liquid and vapor h311 toxic in contact with skin precautionary statements ghs us. Uses advised against not for food, drug, pesticide or biocidal product use details of the supplier of the safety data sheet emergency telephone number chemtreco, inside the usa. Disclaimer the sds samples above are collected from the internet by chemblink and displayed here for the tutorial purpose only.
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